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Anafranil 25mg Tablets 30's (Original Prescription Is Mandatory Upon Delivery) Others Whitens Nourishes ProtectsProduct Description. Anafranil 25mg Tablet is a tricyclic antidepressant. It is used in adults to treat obsessive compulsive disorder (OCD). It also treats muscular weakness (cataplexy) associated with repeat attacks of sleepiness (narcolepsy) and can manage depression that is unresponsive to other medicines. Dosage. Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Anafranil